My Science - Blog / Mein Naturwissenschaftsblog

Hopefully some interesting bits of information extracted from science and non-fiction literature. (For historical reasons there are some poems scattered throughout this blog.) Sachthemen und Sachtexte. (Historisch finden sich auf diesem Blog auch einige Gedichte und Aphorismen.) [Just collecting some exciting bits of information here.] [Eine Sammlung von interessanten Texten, Fragen und Antworten will das hier sein. Nicht mehr, aber auch nicht weniger.]

Dienstag, 29. März 2016

Dopamine Enhances Expectation of Pleasure in Humans

Dopamine Enhances Expectation of Pleasure in Humans
Tali Sharot, Tamara Shiner, Annemarie C. Brown, Judy Fan, and Raymond J. Dolan (2009)

Abstract

Human action is strongly influenced by expectations of pleasure. Making decisions, ranging from which products to buy to which job offer to accept, requires an estimation of how good (or bad) the likely outcomes will make us feel. Yet, little is known about the biological basis of subjective estimations of future hedonic reactions. Here, we show that administration of a drug that enhances dopaminergic function (dihydroxy-L-phenylalanine; L-DOPA) during the imaginative construction of positive future life events subsequently enhances estimates of the hedonic pleasure to be derived from these same events. These findings provide the first direct evidence for the role of dopamine in the modulation of subjective hedonic expectations in humans.

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In seinen lebendigsten Stunden findet der Mensch Erfüllung.

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Der Reiz mancher Gedanken erschöpft sich nicht. An manchen Gedanken können wir wieder und wieder und wieder Anteil nehmen.

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Menschen, die auch im Schmerz noch singen. Denen der Mut nie abhanden kommt.

Freiheit: Die Bestrebung, das "Ich muss" zu entfernen, und, als Ersatz, das "Ich will" zu kultivieren.

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Every scientific field has its distinct population of ideas and statements.