Openness and Schizotypy:

"What Openness and positive schizotypy share is an elevated tendency to perceive patterns and meaning in loosely related stimuli. In positive schizotypy this tendency is taken to an extreme in which patterns may be identified as objectively real even when they are not (a phenomenon also known as “apophenia”). Intelligence may play a key role in determining whether identification of patterns by people high in Openness leads to adaptive cognitive abilities—such as creativity, which is strongly linked to Openness (DeYoung, 2015; Kaufman et al., 2016)— or to the apophenia that characterizes positive schizotypy."

Grazioplene RG et al. - White matter correlates of psychosis-linked traits support continuity between personality and psychopathology, 2016

------

"Broadly speaking, neurostructural and neurofunctional findings indicate that psychotic-spectrum diseases are linked to disrupted or aberrant patterns of neural connectivity. This body of evidence has led to the dysconnectivity theory of psychosis, which states that the core symptoms of psychosis are the result of altered connectivity between brain regions, particularly between specific thalamocortical and frontotemporal regions (Pettersson-Yeo, Allen, Benetti, McGuire, & Mechelli, 2011). Connectivity is typically observed as aberrantly low between these regions (hypoconnectivity), although some specific interconnections may be aberrantly high (hyperconnectivity; e.g., Filippi et al., 2014). Such altered connectivity patterns are thought to lead to abnormal sensory and cognitive integration (Pettersson-Yeo et al., 2011)."